The impact of non-pharmaceutical interventions for 2009 H1N1 influenza on travel intentions: A model of goal-directed behavior.

The impact of non-pharmaceutical interventions for 2009 H1N1 influenza on travel intentions: A model of goal-directed behavior.

Theoretically, in the tourism context this study introduced a new concept of non-pharmaceutical intervention (NPI) for influenza, and tested the impact of NPI on the behavioral intention of potential international tourists. This study also extended the model of goal-directed behavior (MGB) by incorporating the new concepts of NPI, and the perception of 2009 H1N1.

The model found that desire, perceived behavioral control, frequency of past behavior, and non-pharmaceutical interventions predicted tourists’ intention but perceptions of 2009 H1N1 had nil effect on desire and intention. Personal non-pharmaceutical interventions were theorized as adaptive behavior of tourists intending to travel during a pandemic which should be supported by tourism operators on a system-wide basis.

Mouse monoclonal tdTomato antibody, Clone 2H2

E45M08824V-2 50 ul
EUR 195

Mouse monoclonal tdTomato antibody, Clone 4B3

E45M08849V-2 50 ul
EUR 195

Mouse monoclonal tdTomato antibody, Clone OTI4B3

TA180148 100 µl Ask for price

Mouse monoclonal tdTomato antibody, HRP conjugated

TA183004 100 µl Ask for price

Mouse monoclonal tdTomato antibody, Magnetic beads

TA183027 1 ml Ask for price

pLVX- IRES- tdTomato

PVT11066 2 ug
EUR 361.2

2C::tdTomato Reporter

PVT10473 2 ug
EUR 319.2

Carrier-free (BSA/glycerol-free) Mouse monoclonal tdTomato antibody, clone LBI2H2

E45M08824 100 ug
EUR 595

Carrier-free (BSA/glycerol-free) Mouse monoclonal tdTomato antibody, Clone LBI4B3

E45M08849 100 ug
EUR 595

pCDH- EF1- luc2- T2A- Tdtomato Plasmid

PVT2337 2 ug
EUR 289.2

tdTomato Escherichia coli Recombinant Protein

E45O49252E1 250 ug
EUR 314.17

rAAV-CAG-hChR2(H134R)-tdTomato-WPRE-SV40 polyA

PT-0235 1 vial Ask for price
Description: Adeno-associated virus vector.

rAAV-hSyn-DIO-Kir2.1-tdTomato-WPRE-hGH polyA

PT-1745 1 vial Ask for price
Description: Adeno-associated virus vector.

Anti-tdTomato antibody

STJ140002 150 µg
EUR 277.2
Description: Goat polyclonal antibody to tdTomato (red fluorescent protein). tdTomato protein is derived from DsRed, an engineered red fluorescent protein from so-called disc corals of the genus Discosoma. It is a genetic fusion of two copies of the dTomato gene, which has been specifically designed for low aggregation. It´s brightness and emission wavelength makes it ideal for live animal research.

Goat Polyclonal Anti-tdTomato Antibody

AB8181-200 600 µg Ask for price

Anti-Tdtomato chicken polyclonal antibody

TA150089 150 µl Ask for price

anti-tdTomato

AB7358-200 400 µg
EUR 352
Description: Goat polyclonal antibody to tdTomato (red fluorescent protein). tdTomato protein is derived from DsRed, an engineered red fluorescent protein from so-called disc corals of the genus Discosoma. It is a genetic fusion of two copies of the dTomato gene, which has been specifically designed for low aggregation. It is a ~54 kDa protein that is optimally excited at a 554 nm and has a maximum of emission at 581 nm. It´s brightness and emission wavelength, makes it ideal for live animal research.

anti-tdTomato

MBS448092-002mg 0.02mg
EUR 110

anti-tdTomato

MBS448092-06mg 0.6mg
EUR 330

anti-tdTomato

MBS448092-5x06mg 5x0.6mg
EUR 1440

anti-tdTomato

MBS448282-04mg 0.4mg
EUR 330

anti-tdTomato

MBS448282-5x04mg 5x0.4mg
EUR 1440

Anti-tdTomato monoclonal antibody, clone 27E8

CABT-B268 100 µg
EUR 780.15
Description: Rat

Anti-tdTomato, DyLight405

MBS448222-025mg 0.25mg
EUR 360

Anti-tdTomato, DyLight405

MBS448222-5x025mg 5x0.25mg
EUR 1580

Anti-tdTomato, DyLight488

MBS448223-025mg 0.25mg
EUR 360

Anti-tdTomato, DyLight488

MBS448223-5x025mg 5x0.25mg
EUR 1580

Anti-tdTomato, DyLight550

MBS448224-025mg 0.25mg
EUR 360

Anti-tdTomato, DyLight550

MBS448224-5x025mg 5x0.25mg
EUR 1580

Anti-tdTomato, DyLight633

MBS448225-025mg 0.25mg
EUR 360

Anti-tdTomato, DyLight633

MBS448225-5x025mg 5x0.25mg
EUR 1580

Anti-tdTomato, DyLight®405

AB181405-100 250 µg
EUR 385
Description: Goat polyclonal antibody to tdTomato (red fluorescent protein) conjugated to DyLight® 405. tdTomato protein is derived from DsRed, an engineered red fluorescent protein from so-called disc corals of the genus Discosoma. It is a genetic fusion of two copies of the dTomato gene, which has been specifically designed for low aggregation. It´s brightness and emission wavelength, makes it ideal for live animal research.

Anti-tdTomato, DyLight®488

AB181488-100 250 µg
EUR 385
Description: Goat polyclonal antibody to tdTomato (red fluorescent protein) conjugated to DyLight® 488. tdTomato protein is derived from DsRed, an engineered red fluorescent protein from so-called disc corals of the genus Discosoma. It is a genetic fusion of two copies of the dTomato gene, which has been specifically designed for low aggregation. It´s brightness and emission wavelength, makes it ideal for live animal research.

Anti-tdTomato, DyLight®550

AB181550-100 250 µg
EUR 385
Description: Goat polyclonal antibody to tdTomato (red fluorescent protein) conjugated to DyLight® 550. tdTomato protein is derived from DsRed, an engineered red fluorescent protein from so-called disc corals of the genus Discosoma. It is a genetic fusion of two copies of the dTomato gene, which has been specifically designed for low aggregation. It´s brightness and emission wavelength, makes it ideal for live animal research.

Anti-tdTomato, DyLight®633

AB181633-100 250 µg
EUR 385
Description: Goat polyclonal antibody to tdTomato (red fluorescent protein) conjugated to DyLight® 633. tdTomato protein is derived from DsRed, an engineered red fluorescent protein from so-called disc corals of the genus Discosoma. It is a genetic fusion of two copies of the dTomato gene, which has been specifically designed for low aggregation. It´s brightness and emission wavelength, makes it ideal for live animal research.

anti- DNTT,TDT antibody

FNab02488 100µg
EUR 606.3
Description: Antibody raised against DNTT,TDT

anti- DNTT,TDT antibody

FNab02489 100µg
EUR 702
Description: Antibody raised against DNTT,TDT

Anti-DNTT,TDT antibody

PAab02488 100 ug
EUR 426

Anti-DNTT,TDT antibody

PAab02489 100 ug
EUR 494.4

Anti-DNTT,TDT antibody

STJ11100551 50 µl
EUR 471.6
Description: NA

Mouse anti TdT-2 Monoclonal Antibody

MBS460852-01mg 0.1mg
EUR 320

Mouse anti TdT-2 Monoclonal Antibody

MBS460852-5x01mg 5x0.1mg
EUR 1390

PE anti-human TdT Antibody

E16FHPTDT-025 25 tests
EUR 483
Description: Available in various conjugation types.

PE anti-human TdT Antibody

E16FHPTDT-100 100 tests
EUR 1155
Description: Available in various conjugation types.

pEF1伪-tdTomato

PVT10727 2 ug
EUR 361.2

pDC316-mCMV-tdTomato

PVTY00103 2ug
EUR 280

pAAV-IRES-tdTomato

PVTY00132 2ug
EUR 280

pAAV-tdTomato-shRNA

PVTY00158 2ug
EUR 280

pLVX-tdTomato-N1

PVTY00860 2ug
EUR 280

pLVX-IRES-tdTomato

PVTY00870 2ug
EUR 280

pLVX-tdTomato-C1

PVTY01118 2ug
EUR 280

Mouse Anti-Human TdT monoclonal antibody, clone JID782

CABT-L2855 100 µl, 500 µl Ask for price
Description: Mouse

Mouse Anti-Human TdT monoclonal antibody, clone JID782

CABT-L2855-100uL500uL 100 uL, 500 uL
EUR 602.4

rAAV-GfaABC1D-tdTomato-WPREs

PT-4472 1 vial Ask for price
Description: Adeno-associated virus vector.

scAAV-hSyn-tdTomato-WPREs

PT-4708 1 vial Ask for price
Description: Adeno-associated virus vector.

pT7-PTPRF-tdTomato Plasmid

PVT48027 2ug
EUR 280

pLVX-IRES-tdTomato-Neo

PVTY00042 2ug
EUR 280

pLVX-mCMV-tdTomato-puro

PVTY00156 2ug
EUR 280

pLVX-ACE2-IRES-tdTomato

PVT28401 2ug
EUR 280

TdT Antibody

39341-100ul 100ul
EUR 468

TDT antibody

70R-13822 100 ug
EUR 386.4
Description: Affinity purified Rabbit polyclonal TDT antibody

TdT antibody

10R-10566 100 ug
EUR 420
Description: Mouse monoclonal TdT antibody

TDT Antibody

CSB-PA850689XA01DOA-02mg 0.2mg Ask for price
Description: Recombinant Arabidopsis thaliana TDT protein

TDT Antibody

CSB-PA850689XA01DOA-10mg 10mg Ask for price
Description: Recombinant Arabidopsis thaliana TDT protein

TdT Antibody

C15389-100ul 100μl
EUR 217
Description: TdT Rabbit Polyclonal Antibody

TdT Antibody

C15389-50ul 50μl
EUR 143.5
Description: TdT Rabbit Polyclonal Antibody

TdT Antibody

GWB-294FCC 0.5 ml Ask for price

TdT Antibody

E301329 200ul
EUR 275
Description: Available in various conjugation types.

TdT Antibody

E80807-4 100μl
EUR 225
Description: Available in various conjugation types.

TdT Antibody

E80807-9 100μl
EUR 225
Description: Available in various conjugation types.

TdT Antibody

MBS5400051-01mg 0.1mg
EUR 445

TdT Antibody

MBS5400051-5x01mg 5x0.1mg
EUR 1855

TdT Antibody

MBS540121-01mg 0.1mg
EUR 445

TdT Antibody

MBS540121-5x01mg 5x0.1mg
EUR 1855

TDT Antibody

MBS8564689-01mL 0.1mL
EUR 305

TDT Antibody

MBS8564689-01mLAF405L 0.1mL(AF405L)
EUR 565

TDT Antibody

MBS8564689-01mLAF405S 0.1mL(AF405S)
EUR 565

TDT Antibody

MBS8564689-01mLAF610 0.1mL(AF610)
EUR 565

TDT Antibody

MBS8564689-01mLAF635 0.1mL(AF635)
EUR 565

TDT Antibody

MBS8564694-01mL 0.1mL
EUR 305

TDT Antibody

MBS8564694-01mLAF405L 0.1mL(AF405L)
EUR 565

TDT Antibody

MBS8564694-01mLAF405S 0.1mL(AF405S)
EUR 565

TDT Antibody

MBS8564694-01mLAF610 0.1mL(AF610)
EUR 565

TDT Antibody

MBS8564694-01mLAF635 0.1mL(AF635)
EUR 565

TDT Antibody

MBS8565961-01mL 0.1mL
EUR 310

TdT Antibody

MBS856647-01mL 0.1mL
EUR 310

TdT Antibody

MBS857085-01mL 0.1mL
EUR 310

TdT Antibody

MBS857085-01mLAF350 0.1mL(AF350)
EUR 570

TdT Antibody

MBS857085-01mLAF405 0.1mL(AF405)
EUR 570

TdT Antibody

MBS857085-01mLBiotin 0.1mL(Biotin)
EUR 570

TdT Antibody

MBS857085-01mLFITC 0.1mL(FITC)
EUR 570

TdT Antibody

MBS850976-01mL 0.1mL
EUR 345

TdT Antibody

MBS850976-01mLAF405L 0.1mL(AF405L)
EUR 565

TdT Antibody

MBS850976-01mLAF405S 0.1mL(AF405S)
EUR 565

TdT Antibody

MBS850976-01mLAF610 0.1mL(AF610)
EUR 565

TdT Antibody

MBS850976-01mLAF635 0.1mL(AF635)
EUR 565

TdT Antibody

MBS9411117-01mL 0.1mL
EUR 420

TdT Antibody

MBS9411117-5x01mL 5x0.1mL
EUR 1740

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) TDT Polyclonal Antibody

MBS9005818-INQUIRE INQUIRE Ask for price

TdT antibody (PE)

61R-1359 100 ug
EUR 720
Description: Mouse monoclonal TdT antibody (PE)

TdT antibody (PE)

MBS834070-01mg 0.1mg
EUR 1170

TdT antibody (PE)

MBS834070-5x01mg 5x0.1mg
EUR 5125

pLenti-EF1-Puro-Palm-tdTomato

PPL80103-4a 1431bp
EUR 218
Description: pLenti-EF1-Puro

rAAV-CaMkIIa-Tau-tdtomato-WPREs

PT-0591 1 vial Ask for price
Description: Adeno-associated virus vector.

rAAV-CaMKIIa-soma-tDtomato-WPREs

PT-7670 1 vial Ask for price
Description: Adeno-associated virus vector.

pLV3-CMV-MCS-tdTomato Plasmid

PVT47904 2ug
EUR 280

pCMV-tdTomato-SLC5A1-Neo Plasmid

PVT48946 2ug
EUR 280

pCMV-PTPRF-tdTomato-Neo Plasmid

PVT49662 2ug
EUR 280

pCDH-EF1-Luc-T2A-tdTomato

PVTY00167 2ug
EUR 280

TdT KIT Antibody

GWB-Q00471 20 TESTS Ask for price

DNTT,TDT Antibody

abx232488-100g 100 µg
EUR 350

DNTT,TDT Antibody

abx232488-100ug 100 ug
EUR 577.2

DNTT,TDT Antibody

abx232489-100g 100 µg
EUR 350

DNTT,TDT Antibody

abx232489-100ug 100 ug
EUR 661.2

TdT Antibody (FITC)

GWB-4851BB 0.02 mg Ask for price

TdT/DNTT Antibody

MBS851445-01mLAF405L 0.1mL(AF405L)
EUR 565

TdT/DNTT Antibody

MBS851445-01mLAF405S 0.1mL(AF405S)
EUR 565

TdT/DNTT Antibody

MBS851445-01mLAF610 0.1mL(AF610)
EUR 565

TdT/DNTT Antibody

MBS851445-01mLAF635 0.1mL(AF635)
EUR 565

TdT/DNTT Antibody

MBS851445-02mL 0.2mL
EUR 345

TdT Antibody (C-term)

E45R03576G-1 100 ul
EUR 395

TdT Antibody (C-term)

E45R03576G-4 50 ul
EUR 295

TDT Antibody (N-term)

MBS9204526-008mL 0.08mL
EUR 210

TDT Antibody (N-term)

MBS9204526-04mL 0.4mL
EUR 430

TDT Antibody (N-term)

MBS9204526-5x04mL 5x0.4mL
EUR 1910

TdT Antibody (C-term)

MBS9212745-008mL 0.08mL
EUR 210

TdT Antibody (C-term)

MBS9212745-04mL 0.4mL
EUR 430

TdT Antibody (C-term)

MBS9212745-5x04mL 5x0.4mL
EUR 1910

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Practically, this study dealt with the issue of influenza 2009 H1N1 with the study findings and implications providing government agencies, tourism marketers, policy-makers, transport systems, and hospitality services with important suggestions for NPI and international tourism during pandemics.

The impact of non-pharmaceutical interventions for 2009 H1N1 influenza on travel intentions: A model of goal-directed behavior.
The impact of non-pharmaceutical interventions for 2009 H1N1 influenza on travel intentions: A model of goal-directed behavior.

Antiviral Activity of Fritillaria thunbergii extract against Human Influenza Virus H1N1 (PR8) in vitro, in ovo and in vivo.

.Influenza viruses cause respiratory diseases in humans and animals with high morbidity and mortality rates. Conventional anti-influenza drugs are reported to exert side-effects and newly emerging viral strains tend to develop resistance to these commonly used agents. Fritillaria thunbergii (FT) is traditionally used as an expectorant for controlling airway inflammatory disorders.

Here, we evaluated the therapeutic effects of FT extracts against influenza virus type A (H1N1) infection in vitroin ovo, and in vivo. In the post-treatment assay, FT extracts showed high CC50 (7500 µg/ml) indicating low toxicity and exerted moderate antiviral effects, compared to Oseltamivir (SI 50.6 vs. 222) in vitro. Antiviral activity tests in ovo revealed strong inhibitory effects of both FT extract and Oseltamivir against H1N1 replication in embryonated eggs.

Notably, at a treatment concentration of 150 mg/kg, only half the group administered Oseltamivir survived whereas the FT group showed 100% survival, clearly supporting low toxicity of FT extracts. Consistent with these findings, FT-administered mice showed a higher survival rate with lower body weight reduction relative to the Oseltamivir group upon treatment 24 h after viral infection.

Our collective results suggest that FT extracts exert antiviral effects against influenza H1N1 virus without inducing toxicity in vitroin ovo and in vivo, supporting its potential utility as a novel candidate therapeutic drug or supplement against influenza.

MicroRNA-132-3p suppress type I IFN response through targeting IRF1 to facilitate H1N1 influenza A virus infection.

Increasing evidence has indicated that microRNAs (miRNAs) have essential roles in innate immune responses to various viral infections; however, the role of miRNAs in H1N1 influenza A virus (IAV) infection is still unclear. The present study aimed to elucidate the role and mechanism of miRNAs in IAV replication in vitro. Using a microarray assay, we analyzed the expression profiles of miRNAs in peripheral blood from IAV patients. It was found that miR-132-3p was significantly upregulated in peripheral blood samples from IAV patients. It was also observed that IAV infection upregulated the expression of miR-132-3p in a dose and time dependent manner. Subsequently, we investigated miR-132-3p function and found that upregulation of miR-132-3p promoted IAV replication, whereas knockdown of miR-132-3p repressed replication.

Meanwhile, overexpression of miR-132-3p could inhibit IAV triggered INF-α and INF-β production and IFN-stimulated gene (ISG) expression , including myxovirus protein A (MxA), 2´, 5´-oligoadenylate synthetases (OAS), and double stranded RNA-dependent protein kinase (PKR), while inhibition of miR-132-3p enhanced IAV triggered these effects. Of note, interferon regulatory factor 1 (IRF1), a well-known regulator of the type I IFN response, was identified as a direct target of miR-132-3p during HIN1 IAV infection.

Furthermore, knockdown of IRF1 by si-IRF1 reversed the promoting effects of miR-132-3p inhibition on type I IFN response. Taken together, upregulation of miR-132-3p promotes IAV replication by suppressing type I IFN response through its target gene IRF1, suggesting that miR-132-3p could represent a novel potential therapeutic target of IAV treatment.

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