In this review, we identify opportunities for drug discovery in the treatment of COVID-19 and in so doing, provide a rational roadmap whereby pharmacology and pharmacologists can mitigate against the global pandemic. We assess the scope for targetting key host and viral targets in the mid-term, by first screening these targets against drugs already licensed; an agenda for drug re-purposing, which should allow rapid translation to clinical trials.

A simultaneous, multi-pronged approach using conventional drug discovery methodologies aimed at discovering novel chemical and biological means targetting a short-list of host and viral entities should extend the arsenal of anti-SARS-CoV-2 agents.

p38 protein
E20-80079	EnoGene	20ug	EUR 489.6

p38 Antibody
48644-100ul	SAB	100ul	EUR 399.6

p38 Antibody
48644-50ul	SAB	50ul	EUR 286.8

p38 antibody
70R-51505	Fitzgerald	100 ul	EUR 321.6
Description: Purified Polyclonal p38 antibody

p38 antibody
70R-51506	Fitzgerald	100 ul	EUR 344.4
Description: Purified Polyclonal p38 antibody

p38 Antibody
abx236076-100ug	Abbexa	100 ug	EUR 577.2

p38 Antibody
20-abx141038	Abbexa	EUR 427.20 EUR 644.40 EUR 260.40	100 ul 200 ul 30 ul

p38 Antibody
35478-100ul	SAB	100ul	EUR 468

p38 Antibody
20-abx007541	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

p38 Antibody
20-abx133223	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor
E1B1863	EnoGene	1mg	EUR 193.2

anti-Crk p38
YF-PA11088	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38
YF-PA11089	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38
YF-PA11090	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Crk p38

anti-Crk p38
YF-PA23509	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to Crk p38

p38 beta, Active
7763-100	Biovision	each	EUR 5214

p38 beta, Active
7763-5	Biovision	each	EUR 444

p38 beta protein
30R-2875	Fitzgerald	5 ug	EUR 603.6
Description: Purified recombinant Human p38 beta protein

Crk p38 Antibody
AF6323	Affbiotech	200ul	EUR 420

Crk Antibody p38
R31526	NSJ Bioreagents	100 ug	EUR 356.15
Description: CRK, also known as p38, is a protein that in humans is encoded by the CRK gene. This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It is mapped to 17p13.3. The protein participates in the Reelin signaling cascade downstream of DAB1. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of Crk functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

anti-AIMP2/p38
YF-PA15507	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to AIMP2/p38

p38 MAPK Antibody
49379-100ul	SAB	100ul	EUR 399.6

p38 MAPK Antibody
49379-50ul	SAB	50ul	EUR 286.8

p38 MAPK antibody
10R-8422	Fitzgerald	100 ul	EUR 471.6
Description: Mouse monoclonal p38 MAPK antibody

p38 MAPK antibody
70R-33398	Fitzgerald	100 ug	EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody
70R-33400	Fitzgerald	100 ug	EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody
70R-34325	Fitzgerald	100 ug	EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody
70R-34327	Fitzgerald	100 ug	EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK Antibody
ABF6456	Lifescience Market	100 ug	EUR 525.6

p38 MAPK Antibody
abx236077-100ug	Abbexa	100 ug	EUR 577.2

P38 MAPK antibody
20R-2403	Fitzgerald	50 ug	EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK antibody
20R-2950	Fitzgerald	100 ul	EUR 471.6
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody
20R-1572	Fitzgerald	100 ug	EUR 846
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody
20R-2087	Fitzgerald	50 ug	EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody
20R-2088	Fitzgerald	50 ug	EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 delta protein
30R-2868	Fitzgerald	5 ug	EUR 603.6
Description: Purified recombinant Human P38 delta protein

p38 alpha protein
30R-2870	Fitzgerald	5 ug	EUR 603.6
Description: Purified recombinant Human p38 alpha protein

p38 MAPK Antibody
20-abx012798	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

p38 MAPK Antibody
20-abx012875	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

p38 MAPK Antibody
AF6455	Affbiotech	200ul	EUR 420

p38 MAPK Antibody
AF6456	Affbiotech	200ul	EUR 420

p38 MAPK Antibody
AF6457	Affbiotech	200ul	EUR 420

anti- p38 antibody
FNab06076	FN Test	100µg	EUR 606.3
Description: Antibody raised against p38

p38 MAPK Antibody
R20266-0.1ML	NSJ Bioreagents	100ul	EUR 347.65
Description: This recombinant p38 antibody reacts to human p38 MAPK. It may also react to the rat and mouse protein, as predicted by immunogen homology.

p38 (pY182) Antibody
20-abx134951	Abbexa	EUR 460.80 EUR 727.20 EUR 276.00	100 ul 200 ul 30 ul

p38 (pY323) Antibody
20-abx133058	Abbexa	EUR 376.80 EUR 560.40 EUR 243.60	100 ul 200 ul 30 ul

p38 (pT180) Antibody
20-abx009863	Abbexa	EUR 376.80 EUR 560.40 EUR 243.60	100 ul 200 ul 30 ul

AIMP2/p38 Antibody
DF12048	Affbiotech	200ul	EUR 420

p38 alpha-MAPK14
RA15053	Neuromics	100 ug	EUR 631.2

p38 Antibody (MAPK14)
F50496-0.08ML	NSJ Bioreagents	0.08 ml	EUR 140.25
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

p38 Antibody (MAPK14)
F50496-0.4ML	NSJ Bioreagents	0.4 ml	EUR 322.15
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

p38 Blocking Peptide
20-abx061736	Abbexa	EUR 309.60 EUR 460.80	1 mg 5 mg

p38 Blocking Peptide
20-abx062080	Abbexa	EUR 326.40 EUR 493.20	1 mg 5 mg

p38 Blocking Peptide
20-abx161932	Abbexa	EUR 326.40 EUR 493.20	1 mg 5 mg

P38 (411 - 425), M. leprae
5-01677	CHI Scientific	4 x 1mg	Ask for price

p38 Polyclonal Antibody
ABP52112-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody
ABP52112-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody
ABP52112-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody
ABP52113-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody
ABP52113-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody
ABP52113-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody
ABP53838-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody
ABP53838-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody
ABP53838-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody
ABP53839-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody
ABP53839-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody
ABP53839-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody
ABP57354-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody
ABP57354-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody
ABP57354-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody
41305-100ul	SAB	100ul	EUR 302.4

p38 Polyclonal Antibody
41305-50ul	SAB	50ul	EUR 224.4

p38 Polyclonal Antibody
41306-100ul	SAB	100ul	EUR 302.4

p38 Polyclonal Antibody
41306-50ul	SAB	50ul	EUR 224.4

p38 Polyclonal Antibody
ES4837-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody
ES4837-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody
ES4838-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody
ES4838-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody
ES8347-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody
ES8347-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody
ES3111-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody
ES3111-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody
ES3112-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody
ES3112-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit
abx197397-96tests	Abbexa	96 tests	EUR 990

p38-α MAPK-IN-1
HY-18874	MedChemExpress	100mg	EUR 3531.6

Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit
EM1199	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml

p38 MAPK-IN-1
HY-12839	MedChemExpress	5mg	EUR 639.6

p38 MAPK-IN-2
HY-U00324	MedChemExpress	10mg	EUR 4440

CMV Antigen (p65+p38+pp150)
E61Y00202	EnoGene	1mg	EUR 840

p38 MAPK Rabbit pAb
A5521-100ul	Abclonal	100 ul	EUR 369.6

p38 MAPK Rabbit pAb
A5521-200ul	Abclonal	200 ul	EUR 550.8

p38 MAPK Rabbit pAb
A5521-20ul	Abclonal	20 ul	EUR 219.6

p38 MAPK Rabbit pAb
A5521-50ul	Abclonal	50 ul	EUR 267.6

p38 MAPK Rabbit mAb
A4771	Abclonal	20 μL	EUR 18

p38 MAPK Rabbit pAb
A10832-100ul	Abclonal	100 ul	EUR 460.8

p38 MAPK Rabbit pAb
A10832-200ul	Abclonal	200 ul	EUR 664.8

p38 MAPK Rabbit pAb
A10832-20ul	Abclonal	20 ul	EUR 219.6

p38 MAPK Rabbit pAb
A10832-50ul	Abclonal	50 ul	EUR 318

p38 MAPK Rabbit pAb
A14401-100ul	Abclonal	100 ul	EUR 369.6

p38 MAPK Rabbit pAb
A14401-200ul	Abclonal	200 ul	EUR 550.8

p38 MAPK Rabbit pAb
A14401-20ul	Abclonal	20 ul	EUR 219.6

p38 MAPK Rabbit pAb
A14401-50ul	Abclonal	50 ul	EUR 267.6

p38 MAPK Rabbit pAb
A11340-100ul	Abclonal	100 ul	EUR 369.6

p38 MAPK Rabbit pAb
A11340-200ul	Abclonal	200 ul	EUR 550.8

p38 MAPK Rabbit pAb
A11340-20ul	Abclonal	20 ul	EUR 219.6

p38 MAPK Rabbit pAb
A11340-50ul	Abclonal	50 ul	EUR 267.6

p38 MAPK Rabbit pAb
A8038-100ul	Abclonal	100 ul	EUR 369.6

p38 MAPK Rabbit pAb
A8038-200ul	Abclonal	200 ul	EUR 550.8

p38 MAPK Rabbit pAb
A8038-20ul	Abclonal	20 ul	Ask for price

This longer-term strategy would provide a deeper pool of drug choices for future-proofing against acquired drug resistance. Second, there will be further viral threats, which will inevitably evade existing vaccines. This will require a coherent therapeutic strategy which pharmacology and pharmacologists are best placed to provide.

Hunting coronavirus SARS-CoV-2 (2019-nCoV): from laboratory testing back to basic research.

The rapid spread of coronavirus disease COVID-19 in many countries causes citizens of daily inconvenience, and even life-threat for elderly population. The invasion of the main pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; 2019-nCov), into human body causes different levels of impact to various patients. One of the most important issues for COVID-19 is how to defend this virus with the ability to foresee the infected targets.

Thus, we maintain the quarantined essentially as for as others saved from COVID-19. So far, the routine laboratory test to confirm whether infected by SARS-CoV-2/2019-nCov or not is through rRT-PCR (qPCR) with certain sequence regions that recognize SARS-CoV-2/2019-nCoV RNA genome.

The heavy loading of rRT-PCR (qPCR) machine and handling labor have tight-packed the instruments as well as the man power almost in every country. Therefore, the alternative approaches are eagerly waiting to be developed. In this review article, we sort out some state-of-the-art novel approaches that might be applied for a fast, sensitive and precise detection of SARS-CoV-2/2019-nCov not only to help the routine laboratory testing but also to improve effective quarantine.